Laboratory of Alexander Nikitin
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Mouse Pathology

Comprehensive characterization of genetically modified mice is impossible without adequate expertise in comparative mouse pathology.

Image of lung tumor from the Classification of proliferative pulmonary lesions of the mouse: Cancer Res., 64: 2307-2316.

Alexander Nikitin is a human pathologist by training and has over 25 years of experience in mouse pathology. He was a Vice Chair of the Pathology and Laboratory Medicine Standing Committee of the Mouse Models of Human Cancers consortium (1999-2004) and a recipient of the NCRR Midcareer Award in Mouse Pathobiology (2002-2007). He is a member of the Academy of Genomic Pathology and Co-Organizer of Practical Workshop Series on the Pathology of Mouse Models for Human Disease. The first workshop took place in the Jackson Laboratory in 2002. The subsequent meetings were held, respectively, at Cornell University (2003 and 2008), the Jackson Laboratory (2004, 2007, 2009, 2012, 2014, 2016 and 2017), Purdue University (2005), Fred Hutchinson Cancer Research Center, Seattle (2006), the University of Washington Medicine - South Lake Union Campus, Seattle (2010 and 2015), Indianapolis (2011), and Farmington, CT (2013). The 17th workshop will be in the Jackson Laboratory, Bar Harbor, ME on October 01 - 05, 2018.

A graduate course VTBMS/TOX 7010 "Mouse and stem cell pathology" is offered by Alexander Nikitin and colleagues at Cornell.

In addition to support of mouse pathology training, these activities allow for continuous exchange with other experts in the field, and ensure the most comprehensive characterization of mouse genetic models generated in Dr. Nikitin's laboratory.